Examples


Molecular Pathways in Muscle Invasive Bladder Cancer - Novel Predictions


KEGG and Reactome pathways significantly enriched in muscle invasive bladder carcinoma

Download Data

KEGG pathway term
Total # of MIBC-PPI features
Bonferroni p-value
Source
Signaling by SCF-KIT
48
2.5e-31
REACTOME:111040
NGF signalling via TRKA from the plasma membrane
52
8.51e-27
REACTOME:12056
Signalling by NGF
58
1.12e-24
REACTOME:11061
DAP12 signaling
45
1.51e-24
REACTOME:147814
IGF1R signaling cascade
31
4.27e-19
REACTOME:150210
IRS-related events triggered by IGF1R
30
2.01e-18
REACTOME:150203
Neurotrophin signaling pathway
32
1.29e-16
KEGG:04722
Insulin signaling pathway
34
2.38e-16
KEGG:04910
Oxytocin signaling pathway
28
1.8e-09
KEGG:04921
Hippo signaling pathway
27
4.93e-09
KEGG:04390
PKB-mediated events
13
9.79e-09
REACTOME:456
GnRH signaling pathway
20
4.48e-08
KEGG:04912
ARMS-mediated activation
11
6.09e-08
REACTOME:12002
Aldosterone-regulated sodium reabsorption
10
0.000452
KEGG:04960
Adipocytokine signaling pathway
13
0.000605
KEGG:04920
NOD-like receptor signaling pathway
11
0.00266882
KEGG:04621
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
9
0.0200411
REACTOME:75913


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